基本信息:
姓名:周玉美
性别:女
出生日期:1986年6月
职务、职称、社会兼职:
副研究员,兼任中华中医药学会体质分会青年委员,北京中西医结合学会变态反应专业委员会常务理事,世界中医药学会联合会过敏性疾病专业委员会理事。
学习经历:
牛牛扑克-百人牛牛-通比牛牛 中西医结合(免疫学)专业 博士研究生
宁夏医科大学 临床检验诊断学专业(微生物方向) 硕士研究生
工作经历:
2022年至今 牛牛扑克-百人牛牛-通比牛牛 王琦院士课题组 副研究员
2020-2022年 牛牛扑克-百人牛牛-通比牛牛 王琦院士课题组 博士后
2015-2020年 内蒙古医科大学 内蒙古自治区分子生物学重点实验室 助理研究员
招生专业及研究方向:
招生层次:硕士
招生专业:中医体质学
研究方向:中西医结合抗感染免疫及变态反应、过敏性疾病的细胞靶向治疗
承担课题(2019年至今):
2023.01-2025.12 主持国家自然科学基金青年项目1项:基于Neutrophil-DCs-naive T细胞轴研究“脱敏定喘汤”调体治疗中性粒细胞型过敏性哮喘的机制。
2022.01-2025.12 参与牛牛扑克-百人牛牛-通比牛牛 “解码中医”协同攻关项目(800万)。
2021.01-2022.12 主持中国博士后科学基金第69批面上项目1项:基于ILC2-DCs细胞对话研究中药“过敏康”调体预防过敏性疾病作用机制。
2022.01-2025.12 参与国自然面上项目:基于DNAtrap介导EOS-DCs细胞串话研究过敏调体方“异病同防”的机制。
2019.12-2021.12 主持内蒙古医科大学青年基金项目:黄芪多糖对 OVA 抗原在 BALB/c 小鼠中的免疫效果评价 。
2023.01-2023.12 主持牛牛扑克-百人牛牛-通比牛牛 校级项目:基于CCL19/CCR7轴研究脱敏定喘汤调体治疗过敏性哮喘作用机制。
荣获中华中医药学会科学技术奖(“辨体论治”防止过敏性疾病的系列研究及应用) 一等奖 第四参与人
研究成果(2019年至今):
(1)Wang J, Zhou Y, Zhang H, Hu L, Liu J, Wang L, Wang T, Zhang H, Cong L, Wang Q. Pathogenesis of allergic diseases and implications for therapeutic interventions. Signal Transduct Target Ther. 2023 Mar 24;8(1):138.(并列第一作者,Q1区,Nature子刊,IF:39.3)
(2)Zhou Y, Zhao H, Wang T, Zhao X, Wang J, Wang Q. Anti-Inflammatory and Anti-asthmatic Effects of TMDCT Decoction in Eosinophilic Asthma Through Treg/Th17 Balance. Front Pharmacol. 2022 Feb 8;13:819728.(Q2区,IF:5.988)
(3)Zhou Y, Chen X, Zheng Y, Shen R, Sun S, Yang F, Min J, Bao L, Zhang Y, Zhao X, Wang J, Wang Q. Long Non-coding RNAs and mRNAs Expression Profiles of Monocyte-Derived Dendritic Cells From PBMCs in AR. Front Cell Dev Biol. 2021 Feb 9;9:636477.(Q2区,IF:6.684)
(4)Zhou Y, Wang T, Zhao X, Wang J, Wang Q. Plasma Metabolites and Gut Microbiota Are Associated With T cell Imbalance in BALB/c Model of Eosinophilic Asthma. Front Pharmacol. 2022 May 18;13:819747.(Q2区,IF:5.988)
(5)Zhou Y, Hu L, Zhang H, Zhang H, Liu J, Zhao X, Wang J, Wang Q. Guominkang formula alleviate inflammation in eosinophilic asthma by regulating immune balance of Th1/2 and Treg/Th17 cells. Front Pharmacol. 2022 Oct 14;13:978421.(Q2区,IF:5.988)
(6) Yumei Zhou, Yuanqiang Zheng, Yajing Chen, Yajing Li, Xiaoying Sun, Yujuan Huo, and Yanchun Shi, Evaluation of a recombinant bacillus calmette-guérin vaccine expressing P39-L7/L12 of Brucella melitensis: An immunization strategy against brucellosis in BALB/c mice. Materials Express, 2020, 10(3), 350-362. (IF:1.65)
(7)Yumei Zhou, Lengge Si, Zihao Liu, Yanchun Shi, B Agula, Long non-coding RNA ZFAS1 promotes progression of NSCLS via regulating of miR-590-3p. Cell Transplantation. (IF:4.064)
(8) Zhou Y, Zong Y, Liu Z, Zhao H, Zhao X, Wang J. Astragalus Polysaccharides Enhance the Immune Response to OVA Antigen in BALB/c Mice. Biomed Res Int. 2021 Jun 28;2021:9976079. (IF: 3.411)
(9)Yumei Zhou, Yuanqiang Zheng, Yajing Chen, Yanchun Shi, Yin and Yang in escaping from immune system of Brucella. European Journal of Immunology, 2019, 49(S3), 551. (Q2区,IF:5.532)
(10) Shi Y, Zhou Y, Chen Y, Zheng Y. The expression of MicroRNA-146a is related with antibody titers and clinical symptoms in brucellosis patients. European Journal of Immunology, 2019, 49(S3), 551. (Q2区,IF:5.532)
(11)Zheng Y, Zhou Y, Chen Y, Jia Y, Wu L, Shi Y. Evaluation of the cytotoxicity of stearoyl gemcitabine-loaded PLGA nanoparticles to Lewis lung cancer cells. European Journal of Immunology, 2019, 49(S3), 551. (Q2区,IF:5.532)
(12)Zheng Y, Zhou Y, Chen Y, Jia Y, Shi Y. Calmette-Guerin in vaccine development and tumor immunotherapy. European Journal of Immunology, 2019, 49(S3), 551. (Q2区,IF:5.532)
(13)Chen Y, Zhou Y, Zheng Y, Shi Y. Identification of potential critical genes in lung squamous cell carcinoma by bioinformatic analysis. European Journal of Immunology, 2019, 49(S3), 551. (Q2区,IF:5.532)
(14)Zheng Y, Chen Y, Zhou Y, Jia Y, Shi Y. Genetic polymorphism in virB operon, flagella synthesis, and virulence regulating systems might result in the attenuation mechanism of Brucella. melitensis M5-10. European Journal of Immunology, 2019, 49(S3), 551. (Q2区,IF:5.532)
(15)Shi Y, Zheng Y, Zhou Y, Chen Y, Jia Y. Oral 4-(N)-stearoyl gemcitabine nanoparticles inhibit tumor growth in mouse models[A]. European Journal of Immunology, 2019, 49(S3), 551. (Q2区,IF:5.532)
(16)Shi Y, Zheng Y, Zhou Y, Chen Y, Jia Y. Gemcitabine derivative improved antitumor activity and potential to circumvent gemcitabine resistance. European Journal of Immunology, 2019, 49(S3), 551.(Q2区,IF:5.532)
(17)Shi Y, Zheng Y, Zhou Y, Chen Y, Lv L. The effects of Liuweidihuang Pills on the histological changes of liver, kidney and pancreas in KK-Ay mice with spontaneous type 2 diabetes mellitus. European Journal of Immunology, 2019, 49(S3), 551. (Q2区,IF:5.532)
招生邮箱:[email protected]